For the sixteenth time, we organized the symposium “Applied Informatics and Boundaries” (AIS 2021) at the Technical Faculty of Alba Regia, University of Óbuda. The event was attended not only by prominent figures of the Hungarian scientific life, but also that of the field of education and research across the border. The presentation of the scientific results at the conference also revealed the university's international and regional relations in higher education, science and industry, as well as the results of recent developments. The conference will hopefully make a major contribution to increasing the competitiveness of companies in Székesfehérvár and the region, and to meeting the long-term technical research and development needs. In addition to the projects completed in the recent period and the presentation of the scientific results, students with outstanding results in talent management were given the opportunity to present their scientific results. The event was held in English, and an online publication with an ISBN number was published with the lectures and posters at the symposium (http://ais.amk.uni-obuda.hu).